Panhwar MS, et al. - Researchers used the 2013 to 2014 National Inpatient Sample database to determine the impact of influenza infection on morbidity and mortality in patients hospitalized with heart failure (HF). Participants included all adult patients admitted with HF with and without concomitant influenza infection. Propensity score matching was used. Concomitant influenza infection was present in 54,590 of 8,189,119 all-cause hospitalizations in patients with HF. Higher incidence of in-hospital mortality (6.2% vs 5.4%, respectively), acute respiratory failure (36.9% vs 23.1%, respectively), acute respiratory failure requiring mechanical ventilation (18.2% vs 11.3%, respectively), acute kidney injury (AKI; 30.3% vs 28.7%, respectively), and AKI requiring dialysis (2.4% vs 1.8%, respectively) was observed in patients with concomitant influenza. These patients also had longer mean lengths of stay (5.9 days vs 5.2 days, respectively) but similar average hospital costs ($12,137 vs $12,003, respectively).