Dovel k, Shaba F, Offorjebe OA, et al. - Investigators performed a cluster-randomized trial to investigate an HIV self-testing intervention integrated into high-burden outpatient departments in Malawi. The individuals aged 15 years or older from 15 outpatient departments at high-burden health facilities (including health centres, mission hospitals, and district hospitals) were included in central and southern Malawi. They applied constrained randomisation to allocate each cluster (1:1:1) to one of the following groups: standard provider-initiated testing and counselling with no intervention (provider offered during consultations), optimised provider-initiated testing and counselling (with additional provider training and morning HIV testing), and facility-based HIV self-testing (Oraquick HIV self-test, group demonstration and distribution, and private spaces for interpretation and counselling). The results showed that, in Malawi, facility-based HIV self-testing improved HIV testing among outpatients, with minimal risk of adverse events. It was further indicated that facility-based HIV self-testing should be recognised for scale-up in settings with a high unmet requirement for HIV testing.