Keskin M, et al. – The impact on clinical outcomes of adjunctive thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI) was investigated in patients with ST–segment elevation myocardial infarction (STEMI) and large thrombus. No improvement in in–hospital and 3–year all–cause death was reported as a result of adjunctive TA during PPCI in the studied population.

Methods

• Researchers evaluated the impact of adjunctive TA on in-hospital and 3-year clinical outcomes in a total number 627 patients with STEMI and large thrombus in native coronary artery.

Results

• Findings demonstrated that the cumulative 3-year incidence of all-cause death was not significantly different between the groups (91.5% versus 89.0%, log-rank test P=0.347).
• Researchers found that after adjusting for confounders, the risk for all-cause death in the TA group was not significantly lower than in the non-TA group (hazard ratio: 1.11, 95% CI: 0.60 to 3.54, P=0.674).
• They noted that the adjusted risks for target lesion revascularization, non-fatal acute myocardial infarction, stent thrombosis were also not significantly different between the 2 groups.