Zhang F, et al. - This study was undertaken to determine if dynamic monocyte chemoattractant protein-1 (MCP-1) level might be predictors of perceived pain during the first and second phacoemulsification eye surgeries in patients with bilateral cataract. Patients with consecutive bilateral cataracts who underwent bilateral sequential phacoemulsification were enrolled retrospectively. According to findings, the MCP-1 levels in aqueous humor were found to be significantly related to perceived pain during cataract surgery. In patients with bilateral cataracts, dynamic MCP-1 levels could be used as predictors of perceived pain during the first and second phacoemulsification eye surgeries, which could help physicians improve care and make better clinical decisions.