Bochicchio S, Milani P, Urbini LE, et al. - Researchers assessed diurnal changes of the following parameters by using optical coherence tomography angiography (OCTA): vessel density in the peripapillary area (PP-VD) and in the optic nerve head (ONH-VD); thickness of retinal nerve fibre layer (RNFL) and ganglion cell complex (GCC). Only eyes have been included with correct automatic segmentation and good-quality images (scan quality > 7/10). Forty-six eyes were assessed from 28 patients with glaucoma, 53 from 31 patients with ocular hypertension, and 62 from 38 controls. Investigators found that systemic hypertension, age, axial length, daily changes in intraocular pressure or scan quality did not correlate with any of the parameters investigated in daily fluctuations. During the daytime, vessel density, GCC and RNFL were stable, thus corroborating OCTA's clinical relevance regardless of the time of acquisition.