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Distribution of diabetic neovascularization on ultra-widefield fluorescein angiography and on simulated widefield OCT angiography

American Journal of Ophthalmology Dec 06, 2019

Russell JF, Flynn HW, Sridhar J, et al. - In order to ascertain if the widefield (WF) swept-source OCT angiography (SS-OCTA) field of view was adequate for identification of neovascularization (NV) in proliferative diabetic retinopathy (PDR), areas of NV in PDR on ultra-widefield (UWF) fluorescein angiography (FA) were identified and compared with a simulated WF SS-OCTA field of view. All individuals with PDR and UWF FA imaging at the Bascom Palmer Eye Institute over a period of 5.5 years have been identified in this retrospective, consecutive case series. In total, 651 eyes with PDR from 433 individuals had at least 1 UWF FA with NV. NV was the most predominant supertemporally elsewhere in PDR, and 99.4% of treatment-naïve eyes had NV within the simulated field of view of WF SS-OCTA. Such findings, combined with previous research using WF SS-OCTA to identify NV in PDR, indicate that WF SS-OCTA may be the only imaging modality required for PDR diagnosis and longitudinal management.
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