Sangaramoorthy M, Yang J, DeRouen MC, et al. - In view of the observed changes in hepatocellular carcinoma (HCC) incidence and the ethno-demographic landscape, researchers sought to determine the recent HCC incidence patterns and trends in California. From the California Cancer Registry, they assessed 47,992 primary, invasive HCC cases diagnosed between 1988-2014. HCC incidence was higher in all other racial/ethnic groups relative to non-Hispanic Whites (NHWs). The highest incidence rates (IRs) were reported in Vietnamese. The incidence was higher among foreign-born vs U.S.-born Chinese, Japanese, Korean, and Vietnamese. The reverse was observed for Hispanic males while there were no differences by nativity for Hispanic females. NHWs showed the most increased IRs. Among Asians, increased rates were observed in male and female Filipinos and Japanese males, while decreased rates were observed in male and female Koreans and Chinese males. Higher annual percent changes (APCs) were reported for U.S.-born male and female Hispanics and Japanese vs foreign-born, as well as Filipino males, while Chinese males showed a reverse pattern. In recent years, slowing down of annual increases in HCC incidence was noted for U.S.-born Hispanic males and females and male NHWs and non-Hispanic Blacks had stabilized incidence. For some Asian groups, increasing/stable APCs were noted in early time periods while decreasing APCs were reported in later time periods.