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Disease severity and clinical outcomes of community acquired pneumonia caused by non-influenza respiratory viruses in adults: A multicenter prospective registry study from CAP-China Network

European Respiratory Journal Jun 12, 2019

Zhou F, et al. - Among prospectively recruited hospitalised immunocompetent patients with community acquired pneumonia (CAP), researchers looked at the importance of non-influenza respiratory viruses as well as their influence on clinical outcomes. The participants were recruited from 34 hospitals in Mainland China. Influenza and non-influenza viral-infection groups were compared. This study included 915 of 2336 adult patients with viral infection, the most frequently detected was influenza virus (28.4%), followed by respiratory syncytial virus (3.6%), adenovirus (3.3%), human coronavirus (3.0%), parainfluenza virus (2.2%), human rhinovirus (1.8%), and human metapneumovirus (1.5%). The 27.4% of viral pneumonia was attributed to non-influenza viral infections. In non-influenza viral pneumonia, a high incidence of complications was reported. Disease severity and outcomes were similarly influenced by non-influenza viruses vs influenza virus. Based on these findings, they advised CAP caused by non-influenza viruses deserves more attention.
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