Rello P, Del Blanco BG, Ruiz-Meana M, et al. - Experts intended to distinguish gender differences in the composition of coronary thrombus in patients with ST-segment elevation myocardial infarction (STEMI), particularly in the young (age ≤ 55 years). They performed a prospective, multicenter study on individuals with STEMI and coronary thrombus was aspirated immediately before percutaneous coronary intervention applying a suction catheter. They applied histopathology, immunohistochemistry and ELISA techniques for the quantitative determination of fibrin, p-selectin and von Willebrand factor (vWF) within thrombi. They collected thrombi from 100 individuals (50 men and 50 women; 13 women and 13 men of <55 years). Compared with men, women presented similar baseline characteristics and pain-to-balloon elapsed time. The results suggested that thrombi from young women with STEMI displayed a lower content of fibrin, p-selectin and vWF than those from men.