Torgersen J, Taddei TH, Park LS, et al. - Given a substantially higher incidence of hepatocellular carcinoma (HCC) among HIV-infected (HIV⁺) than uninfected persons, researchers sought to examine if, in the setting of HIV infection, HCC is morphologically distinct or more aggressive. From the Veterans Aging Cohort Study, they identified 873 patients with HCC (399 HIV⁺) from 2000 to 2015; of these, 140 HIV⁺ and 178 uninfected persons had undergone liver tissue sampling and had microscopically confirmed HCC. They identified no differences in HCC tumor characteristics or background hepatic parenchyma by HIV status, yet an association of HIV with poorer survival was observed. Of note, pathology reports frequently omitted these characteristics.