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Differences in brain areas affecting language function after stroke

Stroke Aug 09, 2019

Kyeong S, et al. - Because brain areas related with functional enhancement differ between acute and chronic post-stroke phases, researchers examined brain areas related to language function, depending on time after stroke. Aphasia patients following stroke were separated into subacute (≤ 3 months after stroke, 17 patients) and chronic groups (> 12 months after stroke, 23 patients). Findings suggested a positive association of structural connectivity in the left dorsal pathway (eg, superior temporal gyrus, inferior parietal lobule, and superior longitudinal fasciculus) with spontaneous speech, repetition, and naming. On the other hand, structural connectivity in the corona radiata, internal capsule, and corpus callosum of the right hemisphere negatively correlated to language function in the subacute phase. In the bilateral brain areas in the sub-acute phase, but not in the chronic phase, more lateralized language function associated with the dorsal pathway was influenced. During both subacute and chronic phases after stroke, less lateralized language function related to the ventral pathway was impacted in bilateral brain areas.

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