Chen SC, Dastamani A, Pintus D, et al. - Given that diazoxide is first line treatment for hyperinsulinaemic hypoglycaemia (HH), however, diazoxide-induced pulmonary hypertension (PH) can occur, researchers conducted this retrospective cohort study to describe the incidence, and risk factors of diazoxide-induced PH in a large HH cohort to provide recommendations for predicting and preventing PH in diazoxide-treated patients with HH. According to findings, PH may occur in 7% of diazoxide treated HH individuals. Presence of congenital heart disease and fluid overload were included risk factors. Recommendations involve echocardiography and fluid restriction to 130 mls/kg/day before diazoxide treatment and immediate diazoxide discontinuation if PH develops.