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Diagnostic accuracy of interleukin-27 in bronchoalveolar lavage fluids for pulmonary tuberculosis

Infection and Drug Resistance Dec 11, 2019

Lin S, Wang Y, Li Y, et al. - Researchers examined the value of interleukin-27 in bronchoalveolar lavage fluids in diagnosing pulmonary tuberculosis. they determined concentrations of interleukin-27 and adenosine deaminase in 107 bronchoalveolar lavage fluids from patients using enzyme-linked immunosorbent assay. Bronchoalveolar lavage fluids of sputum-positive pulmonary tuberculosis group showed significantly higher concentrations of interleukin-27 relative to those noted in sputum-negative pulmonary tuberculosis, lung cancer, and previous pulmonary tuberculosis groups, respectively. Outcomes support that for the differential diagnosis of pulmonary tuberculosis from lung cancer and previous pulmonary tuberculosis, interleukin-27 in bronchoalveolar lavage fluids is a sensitive and specific biomarker.
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