Li J, et al. - In patients with gastric cancer (GC), researchers created and validated a dual-energy CT based nomogram for the preoperative estimate of lymph node metastasis (LNM) via retrospectively involving 210 surgically confirmed GC patients (159 males, 51 females; mean age: 59.8 ± 7.7 years, range: 28-79 years) who had spectral CT scans and split into a primary cohort (n = 140) and validation cohort (n = 70). Independent predictors of LNM were tumor thickness, Borrmann classification and ICVP. A significant association was noted between the nomogram and LN status. In addition, the nomogram showed a prognostic ability with C-indices of 0.675 for PFS and 0.643 for OS. They presented a dual-energy quantification-based nomogram in this investigation, which can be used to help with the preoperative individualized prediction of LNM in patients with GC.