Gam CMBF, et al. - Given that poor myometrial contractility has been demonstrated in women at term with diabetes and decreased muscular mitochondrial content and/or function has been extensively implicated in the progression of type 2 diabetes, researchers investigated alterations of the uterine mitochondrial phenotype in pregnant women with diabetes as a causal link to decreased myometrial contractility in this observational study. They did not observe indication of decreased mitochondrial function, content, morphology, or localization in the myometrium at term in women with diabetes compared with controls. Findings suggested that the increase in citrate syntase activity in the myometrium could be explained by the lower protein content in the myometrium, which could be due to alterations in tissue or cellular composition.