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Development and validation of risk score to estimate 1-year late poststroke epilepsy risk in ischemic stroke patients

Clinical Epidemiology Aug 29, 2018

Chi NF, et al. - In a National Health Insurance claims-based cohort in Taiwan, researchers included patients initially diagnosed with ischemic stroke between 2003 and 2014 to develop and validate a predictive model for the 1-year risk of late poststroke epilepsy (PSE). To analyze the relationship between 1-year PSE and risk factors before and on stroke admission, multivariable Cox regression with backward elimination was used. Findings revealed that PSEiCARe is an easy-to-use prognostic score that integrates patient characteristics and clinical factors on stroke admission to predict 1-year PSE risk. Prolonged hospital stay (>2 weeks, 1 point), seizure on admission (6 points), elderly patients (age ≥80 years, 1 point), intensive care unit stay on admission (3 points), cognitive impairment (dementia, 2 points), atrial fibrillation (2 points), and respiratory tract infection (pneumonia) on admission (1 point) are the factors included in PSEiCARe, which has the potential to prevent late PSE.

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