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Development and assessment of a novel lung ultrasound interpretation criteria for the detection of interstitial lung disease in systemic sclerosis

Arthritis Care & Research Jun 06, 2020

Fairchild R, Chung M, Yang D, et al. - This study was sought to establish and investigate a novel lung ultrasonography (LUS) examination technique and interpretation criteria for diagnosing systemic sclerosis (SSc)‐interstitial lung disease (ILD). Researchers conducted LUS acquisition by collecting short ultrasound movies at 14 lung positions. They prospectively included SSc patients with high resolution computed tomography imaging within 3 months of LUS to evaluate the performance of the methodology for SSc‐ILD detection. Via two blinded readers (one ultrasonographer and one non‐ultrasonographer), LUS exams were scored independently. They evaluated sensitivity and specificity for SSc‐ILD detection and using Cohen’s Kappa statistic, agreement was assessed. For SSc‐ILD detection, they established a novel LUS examination procedure and interpretation criteria that are highly sensitive and specific in an SSc cohort, affording perfect agreement between ultrasonographer and non‐ultrasonographer readers.

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