Bohula EA, Katz JN, van Diepen S, et al. - Due to an incomplete description of the changing demographics, care patterns, and outcomes in the modern cardiac intensive care unit (CICU), the authors described patients admitted to contemporary, advanced CICUs. The study sample consisted of 3,049 consecutive admitted patients in the Critical Care Cardiology Trials Network (CCCTN), an investigator-initiated network of North American tertiary CICUs. Data reported that the top two CICU admission diagnoses were acute coronary syndrome and heart failure, however, the proportion of acute coronary syndrome was highly variable across centers. Respiratory insufficiency and shock were the most common indications for CICU admission. For many indications, high resource use, and poor outcomes were reported. While practice patterns varied significantly among centers, a significant low-risk population was recognized. Findings suggest that multicenter collaborative networks, like the CCCTN, could be used to help redesign critical cardiac care and test new therapeutic strategies.