Purvis TE, et al. - Via this retrospective study of data of 6931 patients undergoing spinal surgery, researchers sought to characterize the utilization of fresh frozen plasma (FFP) and platelets in spine surgery. In addition, they determined the clinical outcomes following their administration. Perioperative FFP transfusion was received by 1007 (14.5%) patients and platelets were received by 432 (6.2%). FFP was provided to the majority of patients with a liberal international normalized ratio (INR) trigger of >1.7. As per the multivariate analysis, perioperative FFP administration was done in correlation to Charlson Comorbidity Index (CCI) ≥4, preoperative hemoglobin <12 g/dL, preoperative INR ≥1.7, higher estimated blood loss, and receipt of packed red blood cell or platelet transfusion. Receipt of perioperative FFP was noted to be correlated with a higher likelihood of experiencing infection, increased length of stay, and ischemic, respiratory, thrombotic, and renal complications. Independent predictors of experiencing any complication were perioperative FFP, platelet transfusion, American Society of Anesthesiologists grade 3 or 4, CCI≥4, and receipt of packed red blood cells.