Go YY, et al. - In a population-based prospective HF registry (2008–2012), researchers studied 10,363 patients segregated into clusters based on their 3-year heart failure (HF) readmission frequency trajectories, to identify a ‘frequent admitter’ phenotype. Two clusters of HF patients were identified: a high frequency cluster (90.9%, mean 2.35 ± 3.68 admissions/year) and a low frequency cluster (9.1%, mean 0.50 ± 0.81 admission/year). Observations revealed that ‘frequent admitters’, defined as patients with ≥ 2 HF admissions in the index year (n = 2587), were of younger age (68 ± 13 vs 69 ± 13 years), more often male (58% vs 54%), smokers (38.4% vs 34.4%) and had lower left ventricular ejection fraction (37 ± 17 vs 41 ± 17%) compared to ‘non-frequent admitters’ (< 2 HF admissions in the index year; n = 7776). Although the groups had similar rates of advanced care utilization, frequent admitters displayed a longer length of stay (median 4.3 vs 4.0 days), higher annual inpatient costs (€ 7015 vs € 2967) and higher all-cause mortality at 3 years compared to the non-frequent admitters.