Qintar M, et al. - Given that following successful chronic total occlusion (CTO) percutaneous coronary intervention (PCI), many patients often remain on multiple antianginal medications (AAMs) despite the possibility for marked reduction in angina symptom burden after the procedure, researchers investigated how de-escalation of AAMs after CTO PCI impact long-term health status. Using the Seattle Angina Questionnaire and the Rose Dyspnea Scale, they assessed health status at 6 months after successful CTO PCI in a 12-center registry of consecutive CTO PCI patients. Technical success of CTO PCI was reported in 669 patients. De-escalation of AAMs was reported in 276 (35.9%) of these patients at 1 month. The multivariable model did not show correlation of de-escalation of AAMs at 1 month with an increased risk of angina, dyspnea, or worse health status at 6 months after adjusting for complete revascularization and predicted risk of post-PCI angina.