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Correlational analysis between neutrophil granulocyte levels and osteonecrosis of the femoral head

BMC Musculoskeletal Disorders Sep 10, 2019

Jiang J, Liu X, Lai B, et al. - Researchers conducted this retrospective review to explore the association between neutrophil level in the peripheral blood (neutrophil granulocyte) and osteonecrosis of the femoral head (ONFH), a disease with a high rate of disability. Between January 1, 2011, and December 31, 2016, a total of 984 patients [mean age was 59.89 ± 17.06 years (range: 38–82 years)] with ONFH and femoral neck fractures diagnosed at the Department of Orthopedics at the institution were analyzed. There were 488 and 496 cases, respectively, in the ONFH and non-ONFH groups. Neutrophil granulocyte levels and percentage of neutrophil granulocytes were the factors influencing ONFH. Neutrophil granulocyte percentage has a significant correlation with aseptic femoral head necrosis, providing a new perspective and direction for further investigation of femoral head necrosis.
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