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Correlation of clinical illness with viremia in Zika virus disease during an outbreak in Singapore

BMC Infectious Diseases Jul 12, 2018

Ng DHL, et al. - Researchers aimed at describing the clinical characteristics of Zika virus (ZIKV) infection and its correlation to viremia and other laboratory investigations, as observed during the ZIKV outbreak in Singapore. They identified this as the first known paper that examined the correlation of symptoms and signs of viremia in ZIKV disease in an Asian cohort. The duration of ZIKV viremia was identified to have no correlation with the progression of clinical disease or symptoms. In addition, despite the resolution of symptoms and signs, a sizeable proportion of patients were identified to be viremic. Over half the patients displayed hypokalemia suggestive of direct glomerular injury by the virus.
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