Wang D, Li R, Wang J, et al. - In view of the high mortality rate in critically ill patients with COVID-19, researchers sought to determine clinical and biochemical parameters between mild and severe patients, that may aid in early detection of severe and critical patients. They conducted a single center, cross-sectional study including 143 patients. Based on findings, they emphasize closely observing and possibly preventing progression of COVID-19 to critical stage with the help of parameters such as age > 52 years, C-reactive protein > 64.79 mg/L, lactate dehydrogenase > 245 U/L, D-dimer > 0.96 μg/mL, serum amyloid A > 100.02 mg/L, or albumin < 36 g/L. They suggest prognostic value of lymphocyte count, serum potassium, high-density lipoprotein cholesterol and procalcitonin in addition.