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Corneal higher-order aberrations in DMEK vs UT-DSAEK in DETECT: A randomized clinical trial

Ophthalmology Feb 22, 2019

Duggan MJ, et al. - In this randomized controlled clinical trial, authors examined the outcomes of corneal higher-order aberrations (HOA) following ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) vs Descemet membrane endothelial keratoplasty (DMEK). They noticed that the posterior corneal surface had significantly less coma and total HOA in DMEK than UT-DSAEK (4.0- and 6.0-mm OZ) at 3, 6, and 12 months after surgery. They recorded a significant decrease in total posterior HOA at 6 and 12 months (compared to pre-surgical values) in DMEK (4.0- and/or 6.0-mm OZ). They suggested a moderate correlation of total posterior corneal HOA with 6- and 12-month post-operative visual acuity.
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