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Corneal cross-linking in thin corneas: 1-year results of accelerated contact lens–assisted treatment of keratoconus

Journal of Refractive Surgery Oct 20, 2019

Knyazer B, et al. - For patients with keratoconus and thin corneas, researchers conducted this retrospective study to assess the effectiveness and safety of accelerated contact lens–assisted cross-linking (A-CACXL). The study population included consecutive individuals undergoing A-CACXL for progressive keratoconus from 2015 to 2017. Participants in the study were individuals with a minimum corneal thickness of 400 µm or less after epithelium removal who had A-CACXL (9 mW/cm2 for 10 minutes, using iso-osmolar 0.1% riboflavin solution and a 90-µm thick, daily disposable bandage soft contact lens) with a follow-up time of 12 months or more. Overall, 24 patients (24 eyes) were involved with a follow-up time of 18.2 ± 6.3 months and a mean minimum corneal thickness, after epithelial debridement, of 353.13 µm. According to findings, A-CACXL halted keratoconus progression in 80% in patients with keratoconus and thin corneas, led to flattening in 45%, and significantly improved UDVA and keratometry values without any evidence of corneal endothelium damage or permanent adverse events.
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