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Conservative management of low-risk prostate cancer among young vs older men in the United States: Trends and outcomes from a novel national database

Cancer Jul 04, 2019

Mahal AR, et al. - Rates of conservative management for low-risk prostate cancer (LRPC) were determined and related short-term outcomes in young vs older men in the United States were assessed. From the nonpublic Surveillance, Epidemiology, and End Results Prostate with Active Surveillance/Watchful Waiting (AS/WW) Database, 50,302 men diagnosed with LRPC were identified from 2010 through 2015. Patients aged ≤55 years showed a fourfold increase in AS/WW rates from 2010 to 2015, along with favorable short-term outcomes. These findings suggest AS/WW as safe in the short-term and its increasing acceptance among both younger and older patients. However, older patients still display higher absolute rates of AS/WW, implying some national ambivalence toward AS/WW in younger patients.

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