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Comparison of urinary sodium and blood pressure relationship from the spot vs 24-hour urine samples

Journal of the American Heart Association Oct 28, 2019

Naser AM, Rahman M, Unicomb L, et al. - Researchers compared the link between sodium (Na) consumption and blood pressure when they used first- and second-morning spot urine samples to estimate Na consumption [using the INTERSALT (International Study on Salt and Blood Pressure) formula] vs directly measured 24-hour samples. From 383 participants in coastal Bangladesh, they obtained 24-hour urine and first- and second-morning voids for 2 visits. They used an Omron HEM–907 monitor to determine the blood pressure of participants. For the first, second, and for the 24-hour samples, the mean daily urinary Na was estimated to be 122 (SD 26) mmol/d, 122 (SD 27) mmol/d, and 134 (SD 70) mmol/d, respectively. According to the findings, a difference was evident in the link of urinary Na and systolic blood pressure, for 3 urinary Na measurements. More variability of Na consumption was captured by 24-hour urinary Na vs spot urine samples, and the regression models of the former were not influenced by multicollinearity.
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