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Comparison of urinary sodium and blood pressure relationship from the spot vs 24-hour urine samples

Journal of the American Heart Association Oct 24, 2019

Naser AM, Rahman M, Unicomb L, et al. - Researchers compared the link between sodium (Na) consumption and blood pressure when first- and second-morning spot urine samples, vs directly measured 24-hour samples, were used to estimate daily urinary Na excretion. From 383 participants in coastal Bangladesh, 24-hour urine and first- and second-morning voids were obtained for 2 visits. Using an Omron HEM–907 monitor, the measurements of blood pressures of the participants were obtained. For the first, second, and 24-hour samples, the mean daily urinary Na was estimated to be 122 (SD 26) mmol/d, 122 (SD 27) mmol/d, and 134 (SD 70) mmol/d, respectively. For 3 urinary Na measurements, a difference was evident in the urinary Na and systolic blood pressure link. More variability of Na consumption was provided by 24-hour urinary Na vs spot urine samples, and its regression models were not influenced by multicollinearity.
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