Meyer LA, et al. - Researchers assessed the data to analyze the symptom burden and functional recovery in females undergoing primary cytoreductive surgery (PCS) or neoadjuvant chemotherapy (NACT) vs interval cytoreductive surgery (ICS) within an enhanced recovery after surgery program (ERAS) among 196 cases. They observed PCS cases with a significantly higher median surgical complexity score (4 vs 2), and longer median surgical time (257 min vs 220 min). They found no significant discrepancies in symptoms in the immediate in-hospital and extended post-hospital discharge period when subjects undergoing PCS had significantly different symptom burden profiles former to surgery as compared to those undergoing ICS. Subjects undergoing intermediate or high complexity surgery were reported with more nausea, fatigue, and higher total interference scores when compared to outpatients undergoing low complexity surgery irrespective of the timing of surgery in relation to chemotherapy.