Cha SM, et al. - Via performing a prospective comparative trial, researchers investigated the efficacy of mini-open anterograde intramedullary nailing (AIN) vs open reduction and internal fixation using the low-profile locking plate for angulated metacarpal shaft fractures. Investigation of Group 1 (mini-open AIN; 40 patients) and the other consecutive patients in group 2 (locking plate; 35 patients) was done between January 2010 and December 2016. Outcomes suggest that for metacarpal shaft fractures, both mini-open AIN and low-profile plate fixation are excellent options, with no reported significant radiological or clinical problems. However, at 2 years after surgery, patients who underwent mini-open AIN had better several clinical outcomes, such as Disabilities of the Arm, Shoulder, and Hand (DASH) scores and grip strength. Some patients in the low-profile plate group underwent plate removal under anesthesia for various reasons, and this may have led to small discrepancies in the final outcomes evaluated 2 years after surgery.