Schartmüller D, Schwarzenbacher L, Meyer EL, et al. - In this prospective interventional comparative clinical study, researchers compared rotational stability and its influencing factors in three different widely used hydrophobic acrylic intraocular lenses (IOL) from the end of surgery (EoS) to 4 to 7 months (6m) in over 380 eyes. For this investigation, 381 eyes of 199 individuals with age-related cataract received an IOL Acrysof SN60WF, Tecnis ZCB00 or Envista MX60 in consecutive order. Data reported that for the Acrysof, Tecnis, and Envista group, absolute rotations from EoS to 6m were 1.65 ± 2.1, 2.65 ± 4.1and 3.18 ± 5.8 degrees. There was no significant difference between the Tecnis and the Envista groups. Compared with the Tecnis and Envista IOLs, the Acrysof IOL displayed the least amount of absolute rotation. Outliers were found in all groups potentially needing secondary intervention. During the first postoperative hour, the amount of rotation was highest.