Loidolt T, Kurra S, Riew KD, et al. - In this study, the 10-year follow-up adverse events rates between cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) were explored. A randomized, prospective, multicenter Investigational Device Exemption trial was designed to perform single-level surgeries for cervical disc pathologies between May 2002 and October 2004. A total of 463 patients were included in the study (242 individuals received CDA and 221 individuals received ACDF). The results of this study indicate that cumulative rates of individuals who had any adverse events were not different between the artificial cervical disc and the anterior cervical arthrodesis groups. In addition, between the two groups, the cumulative rates were not different for the majority of categories as well.