Liu C, Wang Z, Luo T, et al. - In this prospective cohort study, researchers compared small incision lenticule extraction with prophylactic cross-linking (SMILE Xtra) and femtosecond laser-assisted in situ keratomileusis with prophylactic cross-linking (FS-LASIK Xtra) in their safety, effectiveness, predictability, and stability. Forty-eight eyes subjected to SMILE Xtra and 90 eyes subjected to FS-LASIK Xtra were registered. Data reported that the correlation coefficients for predictability of manifest refractive spherical equivalent (MRSE) correction by SMILE Xtra and FS-LASIK Xtra were 0.987 and 0.983, respectively. The mean MRSE values, keratometry values, and thinnest corneal thickness measured at the different time points exhibited no significant intra- or intergroup variations. The evaluations of 1-year outcomes indicate that the safety, efficacy, predictability, and stability of SMILE Xtra are similar to those of FS-LASIK Xtra.