Corvi F, Cozzi M, Barbolini E, et al. - In the present study, the researchers sought to compare indocyanine green angiography and four different optical coherence tomography angiography (OCTA) devices and to test their reproducibility in the assessment of choroidal neovascularization (CNV). This investigation was an observational case series of Type 1 and Type 2 CNV presenting at the Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, imaged with indocyanine green angiography and four different OCTA devices: prototype PlexElite (Carl Zeiss Meditec), prototype Spectralis OCTA (Spectralis; Heidelberg Engineering, Heidelberg, Germany), Optovue RTVue XR Avanti (Optovue, Inc, Fremont, CA), and AngioPlex (Cirrus 5000 HD-OCT; Carl Zeiss Meditec, Inc, Dublin, CA). Seventeen eyes of 17 patients with CNV have been enlisted. Once imaged with standard indocyanine green angiography, the choroidal neovascularization area is larger than with different OCTA devices that have different algorithms, wavelengths, and scan patterns. The differences in evaluation of quantitative parameters of CNV like CNV area, vessel density, and fractal dimension, between several OCTA devices indicate the need to standardize OCTA measurements for research and clinical practice.