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Comparison between non-visualized polyps and visualized polyps on optical coherence tomography angiography in polypoidal choroidal vasculopathy

Graefe's Archive for Clinical and Experimental Ophthalmology Nov 08, 2019

Zhan Z, Sun L, Jin C, et al. - Researchers sought for underlying reasons for the non-visualization of polyps on en face optical coherence tomography angiography (OCTA) in patients with polypoidal choroidal vasculopathy (PCV). In this cross-sectional study of consecutive treatment-naïve 30 eyes with active PCV, they identified a total of 64 active polyps on fundus fluorescein angiography and indocyanine green angiography (ICGA); 42/64 (65.6%) polyps were visualized while 22/64 (34.4%) polyps were non-visualized on OCTA. As per the analysis, the height of the polyps, and not the size and pulsation of the polyps, was associated with the visualization of the polyps on OCTA. On OCTA, difficulty was faced in visualizing polyps that were pulsating in early ICGA, which may possibly explain the non-visualization. Another reason for the non-visualization of the polyps in active PCV on OCTA was coverage with thick subretinal hemorrhage or retina vessels.
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