McCrabb S, et al. - Researchers conducted a cross-sectional survey of orthopedic trauma patients in two Australian public hospitals to assess their demographic features, smoking status, alcohol consumption, recent cannabis use, and symptoms of anxiety and/or depression. Further, they compared smokers with non-smokers in terms of rates of symptoms and substance use. This population showed high rates of substance use, with tobacco smoking and hazardous drinking higher among a sample of orthopedic trauma patients vs the general population. Cannabis use and symptoms of anxiety and depression were comparable to that of the general population. Current smokers reported significantly higher rates of drinking, cannabis use, and symptoms of anxiety and depression. Further, comorbid substance use was evident in over a fifth (21.8%) of current tobacco smokers. Recent cannabis use was noted among males, who were unmarried, with lower educational attainment and had reported drinking heavily and frequently were current smokers. These findings highlight addressing comorbidities while developing health behavior interventions among the orthopedic trauma population.