Dobkin RD, et al. - In a randomized controlled trial, researchers examined how cognitive-behavioral therapy (CBT) effects different types of depressive symptoms in Parkinson's disease (PD). They investigated if the strongest effect would be seen in cognitive (eg, guilt, rumination, negative attitudes towards self) and behavioral (eg, avoidance, procrastination) symptoms targeted most intensively by the treatment protocol. They randomized 80 depressed people with PD to CBT plus clinical management or clinical management only. Outcomes suggest that a wide range of depressive symptoms in PD could be improved with CBT. The largest change was noted in cognitive and behavioral (vs somatic) symptoms. A combination of CBT and antidepressants was valuable in optimizing the management of somatic complaints in dPD.