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Coagulative biomarkers on admission to the ICU predict acute kidney injury and mortality in patients with septic shock caused by intra-abdominal infection

Infection and Drug Resistance Sep 07, 2019

Xu Z, Cheng B, Fu S, et al. - Researchers examined if acute kidney injury (AKI) and mortality in patients with septic shock caused by intra-abdominal infection (IAI) could be predicted via assessing their coagulative biomarkers on admission to the ICU. They conducted an observational retrospective study that included 138 patients in the surgical ICU; of these patients, 65 developed AKI. AKI occurrence in patients with septic shock caused by IAI was noted to be significantly associated with admission level of activated partial thromboplastin time (APTT), prothrombin time, and D-dimer. Furthermore, there appeared to be an independent predictive value of APTT for 30-day mortality.

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