Lorenzo M, Palau P, Llacer P, et al. - This study was undertaken to investigate if there is a differential impact of length of stay (LOS) on the risk of 6-month acute heart failure (AHF) readmission across carbohydrate 125 (CA125) levels. Researchers designed a retrospective study including a total of 1,387 patients discharged for AHF in two third-level centers. CA125 was measured 48±24 h after admission. They examined the relationship between CA125 and LOS with the risk of subsequent AHF readmission at 6 months by Cox regression analysis accounting for death as a competing event. The results showed that high CA125 levels may identify those patients that benefit from a more prolonged hospitalization in terms of reducing the risk of mid-term AHF readmissions in patients with AHF.