Clinical significance of spleen stiffness in patients with acute decompensated heart failure
ESC Heart Failure Sep 17, 2020
Saito Y, Matsumoto N, Aizawa Y, et al. - Whether spleen stiffness (SS) could quantify the severity of splenic congestion and could predict adverse events in acute decompensated heart failure (ADHF), was determined in this study involving two cohorts: a haemodynamic cohort with 62 heart failure patients and an outcome cohort comprising 115 ADHF patients. Based on the tertile value of SS, experts categorized 115 patients into three groups. The occurrence of adverse events was reported in 25 patients during a median observation span of 105 (77–135) days. A significantly higher rate of adverse events was observed in the third tertile SS group. An independent correlation of a higher SS with adverse events was revealed following adjusting for conventional validated risk score, liver function test, liver stiffness, and estimated right atrial pressure. Overall, experts concluded that degree of SS at discharge can afford a marker of residual splenic congestion, which was identified as a predictor of adverse events in patients experiencing ADHF.
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