de Ávila RE, Fernandes HJ, Barbosa GM, et al. - Via conducting a longitudinal cohort case series study including yellow fever (YF) cases admitted to a Brazilian ICU during the YF outbreaks of 2017 and 2018, researchers sought the factors correlated with YF mortality in these cases. They studied a total of 114 cases (median age:48 years; 92.1% males) and identified a mortality rate of 47.4% among them. YF mortality was identified to be independently correlated to prothrombin time, encephalopathy and APACHE 2. Findings suggest early evolution to liver failure as predictive of higher mortality in YF. No independent association of markers of hepatic inflammation with YF mortality was observed.