Nakayama M, et al. - Authors ascertained the clinical features, treatment and visual outcomes of Japanese patients with new-onset acute Vogt-Koyanagi-Harada (VKH) disease. A presentation of serous retinal detachment and optic disc hyperaemia was seen. Findings suggested that 93.8% of the tested patients were human leucocyte antigen-DR4 positive and 81.8% had cerebrospinal fluid pleocytosis. In 49.5% of eyes, sunset glow fundus was observed and in 22.5% anterior and/or posterior segment recurrence of inflammation was observed. Ocular complications, mostly cataract, were observed in 21.2% and systemic complications, mostly hypertension and diabetes mellitus, were observed in 8.1% of patients. As per data, in a large number of patients with new-onset acute VKH disease, with transitioning to cyclosporine in selected cases an aggressive corticosteroid treatment strategy resulted in excellent visual outcomes and low rates of recurrence.