Reichel H, Zee J, Tu C, et al. - Using a longitudinal observational cohort among German chronic kidney disease (CKD) patients, differences in the patient care and outcomes in real-world nephrology practices were investigated in the Verband Deutsche Nierenzentren and Chronic Kidney Disease Outcomes and Practice Patterns Study, given the lack of research into CKD progression among German patients in a representative setting. From German nephrologist-run CKD clinics, a cohort of CKD Stages 3 (25%) and 4 (75%) patients was instituted in 2013–16. Experts assessed the estimated glomerular filtration rate slope as well as outcomes of end-stage kidney disease (ESKD) and death. According to the findings, routine nephrology care of patients in Germany includes mostly elderly patients, many of those experiencing slow CKD progression. In adjusted models, higher risks of ESKD or mortality were reported for patients with worse kidney function at baseline, male gender, diabetes, and higher blood pressure, and a higher risk of ESKD was observed in relation to higher albuminuria, and a higher risk of death was observed in relation to older age or cardiovascular comorbidity.