Kim YH, Lee B, Kang E, et al. - In this investigation involving 65 patients, researchers sought to explore the connection between choroidal thickness (CT) profile and clinical outcomes after anti-vascular endothelial growth factor (VEGF) treatment in polypoidal choroidal vasculopathy (PCV). Medical records of patients diagnosed with PCV who received anti-VEGF treatment over 12 months have been reviewed. Study participants were divided into different groups based on choroidal profiles including SFCT, nasal PCT (nPCT) and ratio of SFCT to nPCT (SFCT/nPCT). The ratio of SFCT/nPCT exhibited the best predictive ability for poor responders. Such findings indicate that the baseline ratio of nPCT and SFCT/nPCT could be a good biomarker that represents clinical outcomes after anti-VEGF treatment in PCV.