Sethi M, et al. - A retrospective chart review of adult Emergency Department (ED) patients who presented with sepsis was performed to test the hypothesis that higher proportions of balanced resuscitative fluids (BF) during resuscitation would be associated with improved mortality in ED patients with sepsis. As per observations, the proportion of BF during the initial ED resuscitation in septic patients seemed associated with a marked reduction in mortality. This association seemed to provide the necessary rationale for future randomized clinical trials of BF resuscitation in sepsis.