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Characteristics of subjects with undiagnosed COPD based on post-bronchodilator spirometry data

Respiratory Care Jan 04, 2019

Hangaard S, et al. - Since an improved COPD case finding requires a more profound understanding of the characteristics of patients with undiagnosed COPD, researchers used the United States National Health and Nutrition Examination Survey (NHANES) dataset (2007–2012) and studied the characteristics of subjects with undiagnosed COPD based on post-bronchodilator spirometry. Finally, 1,098 subjects with a post-bronchodilator FEV1/FVC < 0.7 or lower limit of normal (LLN) were analyzed. Fewer symptoms and better lung function were seen in subjects with undiagnosed COPD than their diagnosed counterparts. The former group of patients experienced less phlegm (P < .001), wheezing (P < .001), and chest pain (P < .001), less shortness of breath (P < .001), fewer work/school days lost to wheezing (P < .001), less sleep disturbance (P < .001), and less difficulty socializing (P < .001). Moreover, they had higher FEV1 (P < .001), and FVC (P < .001) and were less likely to have asthma (P < .001).
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