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Characteristics of eyes with good visual acuity at 5 years after initiation of treatment for age-related macular degeneration but not receiving treatment from years 3 to 5: Post hoc analysis of the CATT randomized clinical trial

JAMA Ophthalmology Mar 25, 2020

Scoles D, Ying GS, Pan W, et al. - In this case-control study of 625 eyes with neovascular age-related macular degeneration (nAMD), researchers ascertained the characteristics of eyes in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) that retained good vision in spite of receiving no therapy for 3 years after release from the 2-year CATT treatment protocol. The data presented in this work showed a small proportion of eyes with nAMD can retain good visual acuity without treatment for at least 3 years after the initial 2 years of treatment. Unique characteristics of eyes that could discontinue treatment while maintaining good visual acuity could not be established at baseline, but data indicate that care might not be required for all eyes with this disease forever.

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