Inomata T, Iwagami M, Nakamura M, et al. - In this cross-sectional study using crowdsourced data on 4,454 individuals in Japan who downloaded DryEyeRhythm and completed the entire questionnaire, experts evaluated the features and risk factors related to diagnosed and undiagnosed symptomatic dry eye using the smartphone app DryEyeRhythm. The distinguished risk factors for symptomatic vs no symptomatic dry eye were younger age, females, pollinosis, depression, mental illnesses other than depression or schizophrenia, current contact lens use, extended screen exposure, and smoking. The risk factors for undiagnosed vs diagnosed symptomatic dry eye included younger age, males, the absence of collagen disease, mental illnesses other than depression or schizophrenia, ophthalmic surgery other than cataract surgery and laser-assisted in situ keratomileusis, and current or past contact lens use. Thus, findings imply that crowdsourced research recognized people with diagnosed and undiagnosed symptomatic dry eye and their related risk factors. These findings could have a part in more advanced prevention or more efficient interventions for dry eye disease.