Changes of visual fields in treatment of proliferative diabetic retinopathy: A systematic review
Acta Ophthalmologica May 25, 2020
Vergmann AS, et al. - Via conducting a systematic literature search on November 30, 2018 in PubMed and Embase, researchers compared certain side‐effects [visual fields (VF), dark adaptation, colour vision (CV) and contrast sensitivity (CS)] of conventional panretinal photocoagulation (PRP) with those of other treatments in proliferative diabetic retinopathy. A total of 1,867 articles were screened, including 10 studies (2,176 eyes of 2,086 patients examined in VF studies, and 1,360 eyes of 1,360 patients examined in CV and CS studies). Four studies showed a worse VF impact of PRP than vascular endothelial growth factor (VEGF) inhibitors. Overall, the authors observed a trend towards VEGF inhibitors that caused less harm to VF compared with conventional PRP, verified in four large studies. Although VF was generally depressed after laser, there was no difference between different approaches to treatment. In addition, it was not possible to draw certain CV or CS conclusions, with only one study in each field.
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